QPR defenders Anton Ferdinand and Jose Bosingwa will miss the game due to hamstring injuries.
Armand Traore (leg), Andy Johnson (knee) and Fabio (hamstring) are also unavailable.
Stephane Mbia and Adel Taarabt are fit after recovering from their respective groin and hamstring problems, while Kieron Dyer may start his first match since the opening day of last season after impressing as an early substitute at White Hart Lane.
Reading boss Brian McDermott will look to give some of his squad players a run out.
Mali winger Jimmy Kebe could make his first appearance of the season after recovering from a hamstring problem and coming through a practice match unscathed.
Jason Roberts (calf) and Adam Federici (knee) are the two players unavailable to McDermott although Roberts could return at the weekend.
QPR (from): Green, Cesar, Onuoha, Hill, Nelsen, Mbia, Diakite, Derry, Park, Granero, Dyer, Taarabt, Hoilett, Faurlin, Wright-Phillips , Ephraim, Mackie, Zamora, Cisse.
Reading (from): McCarthy, Taylor, Gunter, Cummings, Gorkss, Pearce, Mariappa, Shorey, Harte, McAnuff, Guthrie, Leigertwood, Tabb, McCleary, Kebe, Pogrebnyak, Le Fondre, Hunt, Robson-Kanu, Church.
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